What if a fabric dye from the 1890s could transform your brain health, stop seizures, and boost your mood? On a recent episode of the Joe Rogan Experience, neuroscientist and behavior expert Chase Hughes dropped a bombshell about Methylene Blue, a supplement that changed his life. If you’re searching for the best Methylene Blue supplement, curious about its benefits, or wondering how to take Methylene Blue, this article is your one-stop guide. Stick around to discover why this trending compound is making waves—and how you can get it on Amazon today!
What is Methylene Blue? From Fabric Dye to Brain Booster
Methylene Blue (sometimes misspelled as methalene blue, methaline blue, or methylane blue) started as a textile dye in the 1890s. But its story took a wild turn when scientists injected it into rats and found their brain stems glowing blue. Why? It has a unique affinity for neuronal tissue, meaning it zeroes in on your brain and nervous system like a heat-seeking missile.
Fast forward to today, and Methylene Blue is celebrated as an MAOI (monoamine oxidase inhibitor), a compound that’s been studied for over a century. It’s no longer just methylene dye—it’s a powerhouse supplement with proven uses in medicine and biohacking. Want to dive deeper? Check out its full history on Wikipedia.
Benefits of Methylene Blue: Why It’s Trending
Chase Hughes shared a jaw-dropping story on the podcast: he suffered from temporal lobe epilepsy with mesial temporal sclerosis, enduring up to nine seizures a day. Traditional medications failed him—in fact, one drug’s side effect was more seizures. Enter Methylene Blue, recommended by a functional medicine doctor. The result? His seizures stopped instantly.
But the benefits of Methylene Blue go beyond epilepsy. Here’s what it can do for you:
- Brain Health: As an electron donor to mitochondria, it boosts ATP production (your cells’ energy source) and neutralizes free radicals (those pesky molecules linked to aging and disease). This makes it a potential shield against conditions like Alzheimer’s or CTE, especially if you carry the APOE4 allele, as Hughes mentioned.
- Mood Support: As an MAOI, it regulates neurotransmitters like serotonin and dopamine, helping with depression, anxiety, and life stress.
- Cognitive Power: Users report sharper focus, better memory, and enhanced mental clarity—perfect for students, professionals, or biohackers.
- Cancer Research: Early studies (and whispers on Reddit) suggest Methylene Blue cancer benefits, especially when paired with therapies like red light therapy. While more research is needed, it’s an exciting frontier.
“Is Methylene Blue good for you?” The science—and Chase’s experience—says yes. Curious? RFK Jr. and Mel Gibson have also sung its praises on Rogan’s show.
How to Take Methylene Blue: Dosage, Drops, and Troches
So, how do you take Methylene Blue? Chase Hughes breaks it down:
- Dosage: A common guideline is 1 mg per kilogram of body weight. For a 75 kg (165 lb) person, that’s 75 mg daily. Start low (e.g., 10-20 mg) and adjust based on how you feel. Wondering, “How many drops of Methylene Blue should I take?” If using liquid (typically 1 mg per drop), a 165 lb person might take 75 drops—but always check the product label.
- Forms:
- Liquid Drops: Mix into water (Joe Rogan squirts it into his glass). Brands like MitoZen offer high-quality options.
- Methylene Blue Troche: Hughes uses 40 mg troches (think Starburst consistency). Cut them to your dose and swallow fast to avoid blue teeth!
- Powder: For DIY enthusiasts, though less common.
- Tips: It stains everything—teeth, urine (yes, your pee turns blue), even toilets (Hughes switched to black ones!). Use a straw or rinse your mouth after.
For the best Methylene Blue experience, consistency is key. Take it daily, and pair it with a healthy routine.
Methylene Blue Side Effects: What to Watch For
Methylene Blue is safe for most, with over 100 years of use behind it. But there are caveats:
- Drug Interactions: As an MAOI, it can clash with SSRIs, risking serotonin syndrome. Studies on this were recalled, but caution is wise—consult your doctor if you’re on antidepressants.
- Overdose: Too much (above 80-100 mg) might cause nausea or dizziness. Stick to the recommended Methylene Blue dosage.
- Staining: Not a health risk, but your blue pee might shock party guests (Hughes’ tip: flush!).
No wild side effects unless you mix it with tyramine-rich foods (aged cheese, red wine) at high doses—an MAOI quirk. Overall, it’s a low-risk, high-reward supplement.
Methylene Blue and Red Light Therapy: A Biohacker’s Dream Team
Here’s where it gets wild: red light therapy supercharges Methylene Blue. Why? It’s blue, so it absorbs red light, amplifying its effects on your neurons. Hughes and Rogan (via Gary Brecka) raved about this combo:
- 600x Effectiveness: Okay, Hughes was joking about the exact number, but the boost is real. Your mitochondria soak up more energy, enhancing brain and body performance.
- How-To: Take your Methylene Blue supplement, then hop into a red light therapy session. Devices are available on Amazon.
This duo is trending on X, with users like posting, “Methylene Blue + red light = next-level clarity. Try it!” (October 2023).
Where to Buy Methylene Blue: Amazon’s Got You Covered
Looking for Methylene Blue near me? Skip the hunt—it’s on Amazon! Here are the best Methylene Blue options:
- MitoZen Methylene Blue: Hughes’ go-to brand. Premium quality, available in troches or drops.
- Liquid Methylene Blue Drops: Affordable and easy to dose.
- Best Methylene Blue Supplement: Top-rated for purity and potency.
Who is Chase Hughes? The Brain Behind the Story
Chase Hughes isn’t just a Methylene Blue evangelist—he’s a neuroscience buff (postgrad at Harvard and Duke) and author of Behavior Ops Manual. After 20 years in the military, he turned his focus to behavior, motivation, and self-discipline. His journey? Sparked at 19 by a rejection that led him to study body language—and now he’s a go-to expert.
Hughes’ epilepsy battle (linked to genetics and military concussions) makes his Methylene Blue story even more compelling. Check his book on Amazon for more insights!
Fenbendazole Mention: A Quick Detour
The podcast briefly touched on fenbendazole, an animal dewormer some tout for cancer (see X posts like
’s “Fenbendazole + Methylene Blue = cancer cure?”). But it’s not FDA-approved for humans, and Hughes didn’t use it. Stick to Methylene Blue for now—it’s the star here.
What Does Methylene Blue Do? The Bottom Line
So, what is Methylene Blue? It’s a mitochondrial booster, mood enhancer, and seizure-stopper rolled into one. From Hughes’ recovery to its buzz on X and Reddit, it’s clear: this is no fad. Whether you’re fighting brain fog, stress, or just want to level up, Methylene Blue uses are vast.
Your Next Step: Try Methylene Blue Today
Ready to unlock the Methylene Blue benefits Chase Hughes raves about? Head to Amazon and grab your supply. Start with MitoZen, pair it with red light therapy, and join the thousands transforming their lives.
Resources to Explore
- Behavior Ops Manual by Chase Hughes: Master behavior and discipline.
- Methylene Blue on Wikipedia: The science, unpacked.
- Chase Hughes’ Wikipedia: Meet the man.
Disclaimer: Consult a healthcare professional before starting Methylene Blue, especially if on medication. This article is not medical advice.
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